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October 4, 2021

Bringing Bright Minds Together for the Discovery on Target Conference

The Discovery on Target 2021 conference took place Sept 28-30 in Boston, bringing together several experts from across the US and globally to foster collaboration and share the latest advances in addressing key challenges in drug discovery. At this year’s…


September 29, 2021

How Synthetic Biology Has Shaped the COVID-19 Response

Across the life sciences, researchers have contributed significantly to the response to COVID-19 — elucidating the pathogen, tracking the progression and consequences of infection, and uncovering many of the biological mechanisms associated with patients who display symptoms for months or…


September 15, 2021

In our DNA: Izach Espiritu, Senior Field Service Engineer

We’re continuing our blog series, looking at the DNA of Codex DNA — our incredible employees and their stories. Team member: Izach Espiritu, Senior Field Service Engineer Came aboard: 2014 What do you do at Codex DNA? As a field…


August 25, 2021

A Tour of Key Milestones in Synthetic Biology

Synthetic biology has become so important and widely used that it’s easy to forget how young the field is. Much of the innovation that we rely on today took place in just the last two decades. Codex DNA was originally…


August 18, 2021

In our DNA: Gary Mills, Director of Software Engineering

Team member: Gary Mills, Director of Software Engineering What do you do at Codex DNA? I work on the BioXp™ system, both the 3200 and 3250. My team works on the software and scripting that run the protocols for the…


August 11, 2021

With mRNA Capping Technology, We’re Improving Synthesis Yields

If you’re working with synthetic mRNA, we have exciting news to share. In addition to releasing a new workflow earlier this year that makes it possible to synthesize mRNA form pooled oligos in a single overnight run on our BioXp™…


August 4, 2021

Unlock the potential of BioXp™ automation solutions for bio-fuel production

Our BioXp™ automated end-to-end benchtop system has been used by scientists in many different focus areas to advance breakthroughs in protein engineering. We are delighted to share a great example of utilizing BioXp gene and clone workflows to build recombinant…


July 28, 2021

Happy RNA Day!

RNA Day is on Sunday, August 1st this year, and we welcome the international celebration of one of the most versatile biomolecules we have seen come to life. We have seen RNA play a key role in addressing the COVID-19…


July 21, 2021

In our DNA: Nate Maynard, Director of Biofoundry Services and Reagent Manufacturing

Team member: Nate Maynard, Director of Biofoundry Services and Reagent Manufacturing What do you do at Codex DNA? I work closely with the manufacturing team to build the reagents that create DNA and RNA for the BioXp™ system. We also…


July 14, 2021

How Laura Puga, Codex DNA’s VP of People + Culture, Sees the Future of Work in a Post-Pandemic World

What work do you do at Codex DNA? I work with an amazing team that creates people processes for Codex DNA and facilitates the evolution of our company culture. This function is usually called Human Resources or HR, but we…


July 7, 2021

A Day in The Life: Krishna Kannan, Director of Research and Development

In his scientific career at Codex DNA, Krishna Kannan has led the development of new technologies for our BioXp™ system, allowing us to expand our services and meet customers’ demands. Krishna was also instrumental in bringing the BioXp small-scale mRNA…


June 30, 2021

Codex DNA and MBC Biolabs partner for discovery and automation of synthetic biology applications

We’re thrilled to announce the partnership with MBC Biolabs, a premier biotech incubator in the Bay Area. Under the terms of the collaboration, MBC Biolabs will leverage Codex DNA’s BioXp™ system to empower entrepreneurs in life sciences research with the…


June 23, 2021

Case study: How Cellibre transformed enzyme engineering with Codex DNA

In San Diego, scientists at ag biotech startup Cellibre are looking to replace traditional agriculture for producing high-value ingredients. One of their first targets is the highly valuable cannabinoid market, which they believe can be disrupted by producing natural, high-quality,…


June 16, 2021

RNA Society Conference Recap: Here’s What You Missed

Earlier this month, the Codex DNA team attended the RNA Society conference (all virtual in 2021) to discuss hot topics and relevant content for those responsible for leading their labs through the latest rounds of challenges and crossroads. A benefit…


June 9, 2021

In our DNA: Sarvagya Bhat, Electro-Mechanical Engineer

Team member: Sarvagya Bhat, Electro-Mechanical Engineer What do you do at Codex DNA? I am part of the engineering division at Codex DNA, which is responsible for creating the next generation of products, as well as creating technology for the…


June 2, 2021

PEGS 2021: Protein engineering in the spotlight

Earlier this month the Codex DNA team attended the PEGS Boston Summit, held this year as a virtual event. This important conference has been around for more than 15 years and is well known as a great resource to learn…


May 26, 2021

Scientists use automated DNA synthesis to identify response to antimicrobial threats

Scientists use automated DNA synthesis to identify regulatory mechanism in E. coli response to antimicrobial threats. Bacterial resistance to antibiotics is a looming public health crisis, and scientists continue to investigate how to better characterize the molecular mechanisms underpinning this…


May 19, 2021

Countering emerging SARS-CoV-2 variants webinar recap: Four key takeaways

Last week, we had the opportunity to partner with Jesse Erasmus, Acting Assistant Professor of the University of Washington School of Medicine and Director of Virology at HDT Bio, presenting a webinar titled Development of a replicon RNA vaccine platform…


May 12, 2021

BCC Research podcast recap: Codex DNA on the future of synthetic biology

BCC sits down with Jason Lehmann, PhD, from Codex DNA, Inc. in San Diego to talk about Codex DNA’s mission of applying breakthroughs in synthetic biology automation solutions. BCC podcast host Clara Mouawad and Jason talk about Codex DNA’s recent…


May 5, 2021

We’ve come a long way.

Synthetic biology has advanced rapidly through the years as biologists, physicists, and engineers have continued their efforts to deliver new solutions to global healthcare, agriculture, manufacturing, and environmental challenges. As rapidly as the field is evolving, it’s important to appreciate…


April 28, 2021

Codex DNA presents webinar: Countering emerging SARS-CoV-2 variants with Dr. Jesse Erasmus

The global COVID-19 pandemic caused by the novel SARS-CoV-2 coronavirus created an urgent need for protective interventions. Fortunately, new advances in vaccine development — including nucleic acid-based approaches — have enabled the unprecedented rollout of multiple vaccine products within a…


April 25, 2021

Celebrating DNA Day

We’re celebrating two of the biggest discoveries in scientific history: The molecular structure of DNA and the complete mapping of all genes in the human genome The discovery of DNA’s double helix in 1953 and the completion of the Human…


April 14, 2021

Codex DNA partners with researchers to discover a new way to control citrus greening disease

The bacterial scourge of the citrus greening disease has affected citrus production worldwide, causing tree decline and a serious threat to Florida’s citrus industry. Citrus greening disease, or Huanglongbing (HLB), is caused by Candidotus liberibacter (CLass) and is spread by…


April 7, 2021

In our DNA: Jared Pache, Director of Field Applications

Team member: Jared Pache, Director of Field Applications Came aboard: August 2019 What do you do at Codex DNA? My role is education, assisting our customers with their experimental design, providing applications support, and troubleshooting/technical support. I am involved in…


March 24, 2021

For HIV vaccine study, scientists build pooled variant library using automated DNA synthesis

The quest for an effective vaccine against HIV has spanned decades. While the vaccine itself remains elusive, researchers are making important strides in figuring out how best to design and develop it. Recently, scientists from Duke University and NIH’s Vaccine…


March 17, 2021

Great science: virtual AGBT and ABRF meetings highlight COVID-19 and more

The Codex DNA team loves to get its geek on. For the past year, we’ve missed in-person conferences, but virtual events still let us get up to speed on some of the latest advances in the scientific community. Most recently,…


March 10, 2021

Automated DNA synthesis in the spotlight at SLAS

The Codex DNA team was delighted to participate in this year’s SLAS annual conference, held by the Society for Laboratory Automation and Screening. While our favorite part of the virtual event was getting to interact with the many attendees who…


March 3, 2021

In our DNA: Souriya Sengphet, Program and Solution Architecture Manager

The In our DNA blog series profiles the terrific people who make Codex DNA a truly special place to work, as well as compelling science and technology success stories. Team member: Souriya Sengphet, Program and Solution Architecture Manager Came aboard:…


February 17, 2021

New resource: Biocompare ebook illustrates how life science tools are accelerating COVID-19 research

It can be tough to keep up on the latest COVID-19 news, but a new ebook from Biocompare is here to help. The ebook offers a nice array of articles focused on how novel tools are being used to accelerate…


February 10, 2021

Scientists use Codex DNA technology to discover fever-protective element in malaria parasite

Scientists have made a new discovery that could eventually lead to more effective treatment for malaria. In a series of experiments that included using the BioXp™ system, they determined that a key phospholipid and a related protein confer protection against…


February 3, 2021

In our DNA: Abraham Chen, Senior Customer Service Associate

Team member: Abraham Chen, Senior Customer Service Associate Came aboard: October 2020 What do you do at Codex DNA? In a retail setting, you imagine customer service as a call center or the smiling face behind a counter. However, in…


January 27, 2021

AI-powered design tool and BioXp™ system accelerate metabolic engineering

The next industrial revolution will be biological. By turning cells into factories, synthetic biology changes how we make everything from plastic to food to medicine. But achieving those goals will require overcoming the limitations of DNA design. This is still…


January 20, 2021

Targeted mutagenesis could streamline antibody engineering

Monoclonal antibodies represent an important class of therapies for an ever-increasing number of diseases, infections, and health conditions. That’s why scientists around the world are working to improve the processes required to engineer new antibody candidates for therapeutic use. The…


January 13, 2021

Ready-made SARS-CoV-2 genomes from Codex DNA power development of vaccines, therapies, and diagnostics

Since the start of the COVID-19 pandemic, the Codex DNA team has been working hard to ensure that our customers have access to the tools they need to help in the fight against this public health scourge. We currently offer…


January 6, 2021

In our DNA: Krishna Kannan, Staff Scientist

Today, in our ongoing employee profile series, we catch up with a member of our R&D team. Team member: Krishna Kannan, Staff Scientist Came aboard: November 2019 What do you do at Codex DNA? As part of the R&D team,…


December 30, 2020

2020 in Review: All COVID, all the time (well, almost)

As we are quickly approaching the end of 2020, we’re taking a moment to look back at the year — all 237 months of it. While we hope to never go through another year like this one, we can’t help…


December 23, 2020

T cell engineering: How the BioXp™ system boosts productivity and decreases discovery time

At a recent Oxford Global NextGen Omics UK congress, our own Kirsty Maclean gave a presentation about how the BioXp™ system is powering advances in cell engineering. While she started with a high-level view of how synthetic biology applies to…


December 16, 2020

A vaccine printer at your local drugstore? We are making it happen

You probably know Codex DNA as the developer of the world’s first and only automated benchtop solution for generating gene fragments, clones, and libraries. While we’re incredibly proud of what we’ve accomplished so far, our mission goes well beyond streamlining…


December 9, 2020

BioXp™ system chosen as one of the year’s best innovations by The Scientist

There’s celebrating in the halls — and virtual halls — of Codex DNA. We are truly honored that our new BioXp™ 3250 system was selected as one of the year’s best innovations by The Scientist. This is a very prestigious…


December 2, 2020

Cellibre scientists accelerate enzyme engineering with Codex DNA collaboration

One of the most popular applications of synthetic biology is to confer desired traits to an organism. Designing a range of possibilities and then testing each one for fitness, productivity, stability, or some other goal is critically important as the…


November 24, 2020

In pandemics, rapid DNA synthesis accelerates vaccine development

Back in 2013, I played a small role in response to what then seemed like the next potential pandemic — an outbreak of H7N9, an avian influenza virus. At the time, I was working with Novartis scientists, and we were…


November 18, 2020

Synthetic biology makes a difference in drug discovery

If you were there for the early days of synthetic biology, you probably remember it the way we do: a relatively small number of academic scientists toiling in labs to build key parts, like toggle switches, and tinkering with the…


November 11, 2020

Scientists develop nanobody treatments with the BioXp™ system

In the age of COVID-19, there has been a ton of scientific interest in nanobodies, or single-domain antibodies that can be used for finely targeted viral vaccines. It’s also been a hot topic among users of our BioXp™ system —…


November 4, 2020

Rapid discovery + development of a monoclonal antibody to combat SARS-CoV-2

Without question, the global outbreak of the novel coronavirus 2019 (SARS-CoV-2) that causes COVID-19 has dominated scientific discussion and has been fodder for a wealth of publications as the world urgently races for a better understanding of the mechanism of…


October 28, 2020

Codex DNA celebrates Breast Cancer Awareness Month with great science

Breast cancer is now recognized as the most common malignancy worldwide among women, irrespective of age. Today’s standard of care and breast cancer management relies heavily on chemotherapy, hormone therapy, and targeted therapy. However, there is still much to be…


October 21, 2020

Highlights from the SynBioBeta 2020 Conference

The Codex DNA team really enjoyed attending this year’s virtual Global Synthetic Biology Conference hosted by SynBioBeta. If you missed the event, we’ve got you covered — here’s our take on highlights from the meeting. BioXp™ system in the spotlight…


October 14, 2020

In our DNA: Katie Lyons, Senior Scientist

We’re continuing our blog series, looking at the DNA of Codex DNA — our incredible employees and their stories. Team member: Katie Lyons, Senior Scientist Came aboard: 2008 What do you do at Codex DNA? I develop and adapt biological…


October 6, 2020

Webinar: Rapid synthesis speeds immunotherapy development

For cancer patients with few other treatment options, the need for new targeted immunotherapies is genuinely a matter of life or death. So how to accelerate the development of new therapies? One key component is automated DNA synthesis. That was…


September 30, 2020

Accelerating therapeutic discoveries for lymphoma

The treatment landscape for lymphoma – especially aggressive B-cell lymphomas — has been transformed by adoptive cellular immunotherapy with chimeric antigen receptor (CAR) T cells. Clinical trials with a focus on anti-CD19 CAR-T cell therapy have shown efficacy and long-term…


September 16, 2020

At Oxford conference, automated synthetic biology was in the spotlight

For BioXp™ system users, antibody drug discovery is one of the most popular applications. That’s why we were delighted to participate in the recent Oxford Global Biologics virtual conference, with a presentation from our own Kirsty Maclean, Director of Applications…


September 10, 2020

Biotech scientists use BioXp™ system to streamline antibody drug discovery

Several recent publications from the rockstar team at GigaGen illustrate how they are using the BioXp™ system to streamline antibody drug discovery workflows. It’s tough to overstate the importance of this area of research: monoclonal antibodies, antibody drug conjugates, and…


September 2, 2020

In our DNA: Kirsty Maclean, Director of Applications & Customer Engagement

Today we’re excited to launch a blog series focused on our most valuable resource: our people. We wouldn’t be where we are today — enabling the tremendous science done by our customers — without the Codex DNA family. We’ll be…


August 26, 2020

Meet the BioXp™ 3250 system, our new automated synthetic biology workstation

Please join us in welcoming the newest member of the Codex DNA family. Like its BioXp™ 3200 predecessor, the BioXp™ 3250 system is a fully automated, benchtop platform for synthetic biology workflows — but this one reduces the timelines for…


August 19, 2020

Codex DNA: Building biology for the betterment of all

When it comes to improving life, there is no science more exciting than synthetic biology. The more we learn from reading the DNA or RNA code of every organism on this planet, the better equipped we are to make significant…


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