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Countering emerging SARS-CoV-2 variants webinar recap: Four key takeaways

May 19, 2021  |  Codex DNA

Last week, we had the opportunity to partner with Jesse Erasmus, Acting Assistant Professor of the University of Washington School of Medicine and Director of Virology at HDT Bio, presenting a webinar titled Development of a replicon RNA vaccine platform for response to emerging variants of SARS-CoV-2.

We talked through key attributes for an effective pandemic vaccine, the benefits of nucleic acids as rapid vaccines for pandemics, the process for developing a self-amplifying (replicon), repRNA (VEEV), and LION serving as a highly stable formulation for delivery of RNA vaccine development.

In short, this webinar covered RNA vaccine development fundamentals for every scientist working to address emerging SARS-CoV-2 variants to learn from. And to give you a glimpse, here are some key takeaways from the webinar.

  1. LION/repRNA-CoV2S provides long-lived protective immunity in a non-human primate model of infection
  2. LION is a highly stable formulation for delivery and long-term storage of RNA vaccines that is amenable to rapid scale-up
  3. Multivalent or heterologous prime/boost strategies may be necessary for long-lived broad protective immunity
  4. The BioXp™ system enabled Dr. Erasmus to go from sequence design to synthesizing gene fragments to injecting mice with target vaccine candidates in only eight days

This was a great webinar that offered a wealth of information for those behind developing vaccines and therapeutics for emerging pandemics. If you couldn’t attend, you can view the recording.

View recording

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